Title : N1421K mutation in the glycoprotein Ib binding domain impairs ristocetin- and botrocetin-mediated binding of von Willebrand factor to platelets.

Pub. Date : 2008 Nov

PMID : 18637125






1 Functional Relationships(s)
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1 In vitro mutagenesis and expression in COS-7 cells confirmed the impairment of the mutant in botrocetin- and ristocetin-mediated VWF binding to GPIb. carbonyl sulfide von Willebrand factor Homo sapiens