Title : Interferon-gamma inhibits enterocyte migration by reversibly displacing connexin43 from lipid rafts.

Pub. Date : 2008 Sep

PMID : 18635599






2 Functional Relationships(s)
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1 We show that lipid rafts are required for enterocyte migration, that IFN displaces Cx43 from lipid rafts, and that the phorbol ester phorbol 12-myristate 13-acetate (PMA) restores Cx43 to lipid rafts after treatment with IFN in a protein kinase C-dependent manner. Tetradecanoylphorbol Acetate gap junction protein alpha 1 Homo sapiens
2 We show that lipid rafts are required for enterocyte migration, that IFN displaces Cx43 from lipid rafts, and that the phorbol ester phorbol 12-myristate 13-acetate (PMA) restores Cx43 to lipid rafts after treatment with IFN in a protein kinase C-dependent manner. Tetradecanoylphorbol Acetate gap junction protein alpha 1 Homo sapiens