Title : Bacterial base excision repair enzyme Fpg recognizes bulky N7-substituted-FapydG lesion via unproductive binding mode.

Pub. Date : 2008 Jul 21

PMID : 18635007






1 Functional Relationships(s)
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1 This work shows that Fpg and its eukaryote homolog Ogg1 recognize with high affinity FapydG and bulky N7-benzyl-FapydG (Bz-FapydG). N6-(2-deoxy-erythro-pentofuranosyl)-2,6-diamino-4-hydroxy-5-formamidopyrimidine 8-oxoguanine DNA glycosylase Homo sapiens