Pub. Date : 2008 Sep 12
PMID : 18628202
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Evidence supports a role for UCP3 in fatty acid oxidation (FAO); however, the underlying mechanism has not been explored. | Fatty Acids | uncoupling protein 3 (mitochondrial, proton carrier) | Mus musculus |
| 2 | In 2001 we proposed a role for UCP3 in fatty acid export, leading to higher FAO rates (Himms-Hagen, J., and Harper, M. E. (2001) Exp. | Fatty Acids | uncoupling protein 3 (mitochondrial, proton carrier) | Mus musculus |
| 3 | Specifically, this widely held hypothesis states that during elevated FAO rates, UCP3 exports fatty acid anions, thereby maintaining mitochondrial co-enzyme A availability; reactivation of exported fatty acid anions would ultimately enable increased FAO. | Fatty Acids | uncoupling protein 3 (mitochondrial, proton carrier) | Mus musculus |