Title : Novel N-terminal cleavage of APP precludes Abeta generation in ACAT-defective AC29 cells.

Pub. Date : 2009 Jan

PMID : 18618086






1 Functional Relationships(s)
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Compound Name
Protein Name
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1 Inhibition of acyl-coenzyme A: cholesterol acyltransferase (ACAT), which generates intracellular cholesteryl esters from free cholesterol and fatty acids, reduces the biogenesis of the Abeta from the amyloid precursor protein (APP). Fatty Acids acetyl-Coenzyme A acetyltransferase 1 Mus musculus