Title : Involvement of multiple transporters in the hepatobiliary transport of rosuvastatin.

Pub. Date : 2008 Oct

PMID : 18617601






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Uptake studies revealed that human organic anion transporting polypeptide (OATP) 1B1, OATP1B3, and OATP2B1 accept rosuvastatin as a substrate. Rosuvastatin Calcium solute carrier organic anion transporter family member 1B3 Homo sapiens
2 Among the OATP family transporters, OATP1B1 contributes predominantly to the hepatic uptake of rosuvastatin, as estimated with the previously published relative activity factor method, and OATP1B3 is also partly involved. Rosuvastatin Calcium solute carrier organic anion transporter family member 1B3 Homo sapiens