Title : LXR signaling couples sterol metabolism to proliferation in the acquired immune response.

Pub. Date : 2008 Jul 11

PMID : 18614014






1 Functional Relationships(s)
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1 T cell activation triggers induction of the oxysterol-metabolizing enzyme SULT2B1, consequent suppression of the LXR pathway for cholesterol transport, and promotion of the SREBP pathway for cholesterol synthesis. Oxysterols nuclear receptor subfamily 1, group H, member 2 Mus musculus