| Protein Name | nuclear receptor subfamily 1, group H, member 2 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 22260 |
| Gene Symbol | Nr1h2 |
| UniProt | Q60644 (NR1H2_MOUSE), Q8BP65 (Q8BP65_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
115
Total Number of Articles : 176 |
Description |
nuclear receptor subfamily 1, group H, member 2 |
| Gene Summary |
Enables chromatin DNA binding activity; nuclear receptor activity; and nuclear retinoid X receptor binding activity. Involved in several processes, including negative regulation of metabolic process; positive regulation of transport; and regulation of transcription by RNA polymerase II. Acts upstream of or within lipid metabolic process and regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human NR1H2 (nuclear receptor subfamily 1 group H member 2). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |