Pub. Date : 2008 Oct 1
PMID : 18613030
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Oxysterol-induced osteogenic differentiation of marrow stromal cells is regulated by Dkk-1 inhibitable and PI3-kinase mediated signaling. | Oxysterols | dickkopf WNT signaling pathway inhibitor 1 | Homo sapiens |
| 2 | In addition to activating the hedgehog signaling pathway, oxysterol-induced osteogenic differentiation is mediated through a Wnt signaling-related, Dkk-1-inhibitable mechanism. | Oxysterols | dickkopf WNT signaling pathway inhibitor 1 | Homo sapiens |
| 3 | These oxysterol effects, which occurred in the absence of beta-catenin accumulation or TCF/Lef activation, were inhibited by the hedgehog pathway inhibitor, cyclopamine, and/or by the Wnt pathway inhibitor, Dkk-1. | Oxysterols | dickkopf WNT signaling pathway inhibitor 1 | Homo sapiens |