Title : Prostacyclin induction by high-density lipoprotein (HDL) in vascular smooth muscle cells depends on sphingosine 1-phosphate receptors: effect of simvastatin.

Pub. Date : 2008 Jul

PMID : 18612546






1 Functional Relationships(s)
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Protein Name
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1 Finally, suramin, JTE013 and VPC23019 inhibited p38 MAPK and ERK1/2 signaling pathways activated by HDL (or S1P) and the downstream activation of CREB, a key transcription factor involved in Cox-2 transcriptional up-regulation. Suramin mitogen-activated protein kinase 3 Homo sapiens