Title : Synthesis and antiproliferative activity of substituted diazaspiro hydantoins: a structure-activity relationship study.

Pub. Date : 2009 Apr

PMID : 18607541






1 Functional Relationships(s)
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1 From the SAR studies, it reveals that, the substitution at N-terminal in hydantoin ring plays key role in the antiproliferative activity. Hydantoins sarcosine dehydrogenase Homo sapiens