Title : Coordinate regulation of human drug-metabolizing enzymes, and conjugate transporters by the Ah receptor, pregnane X receptor and constitutive androstane receptor.

Pub. Date : 2009 Feb 15

PMID : 18606396






1 Functional Relationships(s)
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Protein Name
Organism
1 Two major groups of ligand-activated nuclear receptors/xenosensors evolved: the Ah receptor (activated by aryl hydrocarbons and drugs such as omeprazole) and type 2 steroid receptors such as PXR and CAR, activated by drugs such as rifampicin, carbamazepin and phenytoin. Carbamazepine nuclear receptor subfamily 1 group I member 2 Homo sapiens