Pub. Date : 2008 Sep
PMID : 18602458
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | These results demonstrate that low concentrations of the known ototoxic solvents ethylbenzene and p-xylene inhibit alpha9alpha10 nAChR-mediated ion currents, whereas the structurally related, non-ototoxic solvents m-xylene and o-xylene do not, indicating that the alpha9alpha10 nAChR is a potential target for solvent-induced ototoxicity. | 2-xylene | cholinergic receptor nicotinic alpha 4 subunit | Homo sapiens |