Title : Air pollution exposure potentiates hypertension through reactive oxygen species-mediated activation of Rho/ROCK.

Pub. Date : 2008 Oct

PMID : 18599801






1 Functional Relationships(s)
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1 Aortic vasoconstriction to phenylephrine was potentiated with exaggerated relaxation to the Rho-kinase (ROCK) inhibitor Y-27632 and increase in ROCK-1 mRNA levels in the PM(2.5)-AII group. Phenylephrine angiotensinogen Homo sapiens