Title : Carbonyl cyanide p-(trifluoromethoxy) phenylhydrazone (FCCP) as an O2(*-) generator induces apoptosis via the depletion of intracellular GSH contents in Calu-6 cells.

Pub. Date : 2009 Feb

PMID : 18585819






1 Functional Relationships(s)
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1 Treatment with thiol antioxidants, NAC and DTT, showed the recovery of GSH depletion and the reduction of O(2)(*-) levels in FCCP-treated cells, which were accompanied by the inhibition of apoptosis. Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone synuclein alpha Homo sapiens