Title : Brain insulin growth factor-I induces diuresis increase through the inhibition of arginin-vasopressin release in aged rats.

Pub. Date : 2010 Mar

PMID : 18571773






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1 By using osmotic pumps, we have shown that in aged rats, IGF-I treatment in the third ventricle for four weeks increases water intake and restores diuresis and AVP plasma release similar with that observed in adults. Water insulin-like growth factor 1 Rattus norvegicus