Title : Genetic variability in nicotinic acetylcholine receptors and nicotine addiction: converging evidence from human and animal research.

Pub. Date : 2008 Nov 3

PMID : 18571741






3 Functional Relationships(s)
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1 Similarly, research in mice has provided evidence that naturally occurring variability in nAChR genes is associated with changes in nicotine sensitivity. Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
2 Furthermore, the use of genetic knockout mice has allowed researchers to determine the nAChR genes that mediate the effects of nicotine, whereas research with knockin mice has demonstrated that changes to nAChR genes can dramatically alter nicotine sensitivity. Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
3 Furthermore, the use of genetic knockout mice has allowed researchers to determine the nAChR genes that mediate the effects of nicotine, whereas research with knockin mice has demonstrated that changes to nAChR genes can dramatically alter nicotine sensitivity. Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus