Title : The transcription factor Nrf2 is a therapeutic target against brain inflammation.

Pub. Date : 2008 Jul 1

PMID : 18566435






1 Functional Relationships(s)
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1 Animals treated with sulforaphane displayed a 2-3-fold increase in heme oxygenase-1, a reduced abundance of microglial cells in the hippocampus and an attenuated production of inflammation markers (inducible NO synthase, IL-6, and TNF-alpha) in response to LPS. sulforaphane interleukin 6 Mus musculus