Pub. Date : 2008 Jul
PMID : 18565339
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Glycine attenuates endotoxin-induced liver injury by downregulating TLR4 signaling in Kupffer cells. | Glycine | toll-like receptor 4 | Mus musculus |
| 2 | Consistent with these in vivo experiments, enhanced secretion of IL-10 and inhibited expression of TLR4 and TNF-alpha caused by glycine pretreatment were also observed in LPS-stimulated KCs. | Glycine | toll-like receptor 4 | Mus musculus |
| 3 | The downregulative effect of glycine on the endotoxin signaling pathway and TLR4/NF-kappaB/TNF-alpha may be a novel potential mechanism by which glycine inhibits KC activity. | Glycine | toll-like receptor 4 | Mus musculus |