Title : Cis-acting genomic elements of the Pas1 locus control Kras mutability in lung tumors.

Pub. Date : 2008 Sep 25

PMID : 18560355






1 Functional Relationships(s)
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1 Herein, we examined urethane-induced lung tumorigenesis in a new mouse model developed by replacing the Kras gene with an Hras gene in the susceptible A/J-type Pas1 locus and crossing these mice with either C57BL/6J or A/J mice. Urethane Harvey rat sarcoma virus oncogene Mus musculus