Title : The common P446L polymorphism in GCKR inversely modulates fasting glucose and triglyceride levels and reduces type 2 diabetes risk in the DESIR prospective general French population.

Pub. Date : 2008 Aug

PMID : 18556336






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 OBJECTIVE: Hepatic glucokinase (GCK) is a key regulator of glucose storage and disposal in the liver, where its activity is competitively modulated, with respect to glucose, by binding to glucokinase regulatory protein (GCKR) in the presence of fructose 6-phosphate. fructose-6-phosphate glucokinase regulator Homo sapiens
2 OBJECTIVE: Hepatic glucokinase (GCK) is a key regulator of glucose storage and disposal in the liver, where its activity is competitively modulated, with respect to glucose, by binding to glucokinase regulatory protein (GCKR) in the presence of fructose 6-phosphate. fructose-6-phosphate glucokinase regulator Homo sapiens