Title : Effects of N-acetyltransferase 2 (NAT2), CYP2E1 and Glutathione-S-transferase (GST) genotypes on the serum concentrations of isoniazid and metabolites in tuberculosis patients.

Pub. Date : 2008 May

PMID : 18544910






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Acetylating pathway of INH to acetyl isoniazid (AcINH) tended to shift to the hydrolytic pathway generating hydrazine (Hz) with the increase of mutant alleles in NAT2 gene. hydrazine N-acetyltransferase 2 Homo sapiens