Title : The nonsynonymous Thr105Ile polymorphism of the histamine N-methyltransferase is associated to the risk of developing essential tremor.

Pub. Date : 2008

PMID : 18543121






1 Functional Relationships(s)
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1 CONCLUSION: These results, combined with previous findings indicating alterations in the frequency for the HNMT Thr105Ile polymorphism in patients with PD, suggest that alterations of histamine homeostasis in the SNC are associated with the risk of movement disorders. Histamine histamine N-methyltransferase Homo sapiens