Title : The gp130/STAT3 signaling pathway mediates beta-adrenergic receptor-induced atrial natriuretic factor expression in cardiomyocytes.

Pub. Date : 2008 Jul

PMID : 18537819






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Here, we demonstrate that the beta-AR agonist isoproterenol potently evokes the tyrosine phosphorylation of STAT3 and increases its transcriptional activity in an extracellularly regulated kinase 1/2 and glycoprotein (gp)130 signaling-dependent manner in rat cardiomyocytes. Tyrosine signal transducer and activator of transcription 3 Rattus norvegicus