PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18537819-3 2008 Here, we demonstrate that the beta-AR agonist isoproterenol potently evokes the tyrosine phosphorylation of STAT3 and increases its transcriptional activity in an extracellularly regulated kinase 1/2 and glycoprotein (gp)130 signaling-dependent manner in rat cardiomyocytes. Tyrosine 80-88 signal transducer and activator of transcription 3 Rattus norvegicus 108-113