Title : Huperzine A exhibits anti-inflammatory and neuroprotective effects in a rat model of transient focal cerebral ischemia.

Pub. Date : 2008 Aug

PMID : 18513368






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Huperzine A, a reversible and selective acetylcholinesterase (AChE) inhibitor, has been reported to display neuroprotective properties. huperzine A acetylcholinesterase Rattus norvegicus
2 Huperzine A, a reversible and selective acetylcholinesterase (AChE) inhibitor, has been reported to display neuroprotective properties. huperzine A acetylcholinesterase Rattus norvegicus
3 Along with inhibiting AChE activity, huperzine A inhibited nuclear translocation of transcription factor nuclear factor-kappa B, decreased overexpression of proinflammatory factors in both ipsilateral cortex and striatum, and suppressed activation of glial cells in the ischemic penumbra. huperzine A acetylcholinesterase Rattus norvegicus