Title : A cytosolic iron chaperone that delivers iron to ferritin.

Pub. Date : 2008 May 30

PMID : 18511687






8 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Human poly (rC)-binding protein 1 (PCBP1) increased the amount of iron loaded into ferritin when expressed in yeast. Iron poly(rC) binding protein 1 Homo sapiens
2 Human poly (rC)-binding protein 1 (PCBP1) increased the amount of iron loaded into ferritin when expressed in yeast. Iron poly(rC) binding protein 1 Homo sapiens
3 PCBP1 bound to ferritin in vivo and bound iron and facilitated iron loading into ferritin in vitro. Iron poly(rC) binding protein 1 Homo sapiens
4 PCBP1 bound to ferritin in vivo and bound iron and facilitated iron loading into ferritin in vitro. Iron poly(rC) binding protein 1 Homo sapiens
5 Depletion of PCBP1 in human cells inhibited ferritin iron loading and increased cytosolic iron pools. Iron poly(rC) binding protein 1 Homo sapiens
6 Depletion of PCBP1 in human cells inhibited ferritin iron loading and increased cytosolic iron pools. Iron poly(rC) binding protein 1 Homo sapiens
7 Thus, PCBP1 can function as a cytosolic iron chaperone in the delivery of iron to ferritin. Iron poly(rC) binding protein 1 Homo sapiens
8 Thus, PCBP1 can function as a cytosolic iron chaperone in the delivery of iron to ferritin. Iron poly(rC) binding protein 1 Homo sapiens