Title : In vitro and in vivo evaluation of ellagic acid on melanogenesis inhibition.

Pub. Date : 2000 Aug

PMID : 18503416






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 When mushroom-derived tyrosinase, a metaloprotein containing copper, was incubated with EA, enzymatic activity tended to decrease with decreasing copper concentration. Copper tyrosinase Mus musculus
2 When mushroom-derived tyrosinase, a metaloprotein containing copper, was incubated with EA, enzymatic activity tended to decrease with decreasing copper concentration. Copper tyrosinase Mus musculus
3 Tyrosinase activity in the B16 melanoma cells was observed to recover in a dose-dependent manner when copper ions were added to the medium containing EA. Copper tyrosinase Mus musculus
4 Based on these results, EA is thought to react specifically with the copper located at the active centre of the tyrosinase molecule. Copper tyrosinase Mus musculus