Pub. Date : 2008 Aug
PMID : 18496818
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Epigallocatechin gallate (EGCG) attenuates high glucose-induced insulin signaling blockade in human hepG2 hepatoma cells. | epigallocatechin gallate | insulin | Homo sapiens |
| 2 | Epigallocatechin gallate (EGCG) attenuates high glucose-induced insulin signaling blockade in human hepG2 hepatoma cells. | epigallocatechin gallate | insulin | Homo sapiens |
| 3 | In the present study, the investigations of EGCG on insulin signaling are performed in insulin-responsive human HepG2 cells cotreated with high glucose. | epigallocatechin gallate | insulin | Homo sapiens |
| 4 | In the present study, the investigations of EGCG on insulin signaling are performed in insulin-responsive human HepG2 cells cotreated with high glucose. | epigallocatechin gallate | insulin | Homo sapiens |
| 5 | However, the treatment of EGCG improves insulin-stimulated downsignaling by reducing IRS-1 Ser307 phosphorylation. | epigallocatechin gallate | insulin | Homo sapiens |
| 6 | Together, our data suggest a putative link between high glucose and insulin resistance in HepG2 cells, and the EGCG treatment attenuates insulin signaling blockade by reducing IRS-1 Ser307 phosphorylation through the AMPK activation pathway. | epigallocatechin gallate | insulin | Homo sapiens |
| 7 | Together, our data suggest a putative link between high glucose and insulin resistance in HepG2 cells, and the EGCG treatment attenuates insulin signaling blockade by reducing IRS-1 Ser307 phosphorylation through the AMPK activation pathway. | epigallocatechin gallate | insulin | Homo sapiens |