Title : Genetic aspects of epitestosterone formation and androgen disposition: influence of polymorphisms in CYP17 and UGT2B enzymes.

Pub. Date : 2008 Jun

PMID : 18496127






2 Functional Relationships(s)
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1 Genetic aspects of epitestosterone formation and androgen disposition: influence of polymorphisms in CYP17 and UGT2B enzymes. Epitestosterone cytochrome P450 family 17 subfamily A member 1 Homo sapiens
2 RESULTS: A T>C (A1>A2) promoter polymorphism in the CYP17 gene was associated with the urinary glucuronide levels of epitestosterone and its putative precursor androstene-3beta, 17alpha-diol, resulting in 64% higher T/E ratios in A1/A1 homozygotes. Epitestosterone cytochrome P450 family 17 subfamily A member 1 Homo sapiens