Title : Phospholipidosis and down-regulation of the PI3-K/PDK-1/Akt signalling pathway are vitamin E inhibitable events associated with 7-ketocholesterol-induced apoptosis.

Pub. Date : 2009 Jan

PMID : 18495460






1 Functional Relationships(s)
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1 This oxysterol also induces important changes in lipid content and/or organization of the cytoplasmic membrane demonstrated with merocyanine 540 and fluorescence anisotropy, a loss of PI3-K activity and dephosphorylation of PDK-1 and Akt. Oxysterols AKT serine/threonine kinase 1 Homo sapiens