Title : Glutathione as a depigmenting agent: an overview.

Pub. Date : 2005 Jun

PMID : 18492181






1 Functional Relationships(s)
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1 Proposed mechanisms of action include: (a) direct inactivation of the enzyme tyrosinase by binding with the copper-containing active site of the enzyme; (b) mediating the switch mechanism from eumelanin to phaeomelanin production; (c) quenching of free radicals and peroxides that contribute to tyrosinase activation and melanin formation; and d) modulation of depigmenting abilities of melanocytotoxic agents. eumelanin tyrosinase Homo sapiens