Pub. Date : 2008 Jul
PMID : 18491043
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Molecular understanding of copper and iron interaction with alpha-synuclein by fluorescence analysis. | Iron | synuclein alpha | Homo sapiens |
| 2 | Redox-active metal ions such as iron (Fe) and copper (Cu) are known to enhance alpha-synuclein fibrillogenesis. | Iron | synuclein alpha | Homo sapiens |
| 3 | Redox-active metal ions such as iron (Fe) and copper (Cu) are known to enhance alpha-synuclein fibrillogenesis. | Iron | synuclein alpha | Homo sapiens |
| 4 | In the present investigation, we analyzed the binding efficiency of Cu and Fe to alpha-synuclein by fluorescence studies. | Iron | synuclein alpha | Homo sapiens |
| 5 | It is interesting to note that Cu and Fe showed differential binding pattern toward alpha-synuclein (wild type and A30P, A53T, and E46K mutant forms) as revealed by intrinsic tyrosine fluorescence, thioflavin-T fluorescence, 1-anilino-8-naphthalenesulfonate-binding studies, and scatchard plot analysis. | Iron | synuclein alpha | Homo sapiens |