Pub. Date : 2008 Jul
PMID : 18486908
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Ursolic acid induces apoptosis by activating p53 and caspase-3 gene expressions and suppressing NF-kappaB mediated activation of bcl-2 in B16F-10 melanoma cells. | ursolic acid | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
2 | All these results demonstrate that ursolic acid induce apoptosis via inhibition of NF-kappaB induced bcl-2 mediated anti-apoptotic pathway and subsequent activation of p53 mediated and TNF-alpha induced caspase-3 mediated pro-apoptotic pathways. | ursolic acid | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |