Title : SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase.

Pub. Date : 2008 Jul 18

PMID : 18482975






2 Functional Relationships(s)
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1 Polyphenols substantially prevent the impairment in phosphorylation of AMPK and its downstream target, ACC (acetyl-CoA carboxylase), elevation in expression of FAS (fatty acid synthase), and lipid accumulation in human HepG2 hepatocytes exposed to high glucose. Polyphenols fatty acid synthase Homo sapiens
2 Polyphenols substantially prevent the impairment in phosphorylation of AMPK and its downstream target, ACC (acetyl-CoA carboxylase), elevation in expression of FAS (fatty acid synthase), and lipid accumulation in human HepG2 hepatocytes exposed to high glucose. Polyphenols fatty acid synthase Homo sapiens