Title : Analysis of Multidrug Transporter in Living Cells. Inhibition of P-glycoprotein-mediated Efflux of Anthracyclines by Ionophores.

Pub. Date : 1994

PMID : 18476229






1 Functional Relationships(s)
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1 We here report that mobile ionophores such as valinomycin, nonactin, nigericin, monensin, calcimycin, lasalocid inhibit the efflux of anthracycline by P-glycoprotein whereas, channel-forming ionophores such as gramicidin do not. Valinomycin ATP binding cassette subfamily B member 1 Homo sapiens