Title : Cysteine cathepsins trigger caspase-dependent cell death through cleavage of bid and antiapoptotic Bcl-2 homologues.

Pub. Date : 2008 Jul 4

PMID : 18469004






2 Functional Relationships(s)
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1 Cysteine cathepsins trigger caspase-dependent cell death through cleavage of bid and antiapoptotic Bcl-2 homologues. Cysteine BCL2 apoptosis regulator Homo sapiens
2 Moreover, in vitro experiments showed that one or more of the cysteine cathepsins B, L, S, K, and H could cleave Bcl-2, Bcl-xL, Mcl-1, Bak, and BimEL, whereas no Bax cleavage was observed. Cysteine BCL2 apoptosis regulator Homo sapiens