Title : p38 MAP kinase mediates arsenite-induced apoptosis through FOXO3a activation and induction of Bim transcription.

Pub. Date : 2008 Jun

PMID : 18465250






2 Functional Relationships(s)
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1 Sodium arsenite induces apoptosis in PC12 cells by activating the stress-activated p38 MAP kinase and the pro-apoptotic Bcl-2 family protein Bim(EL). sodium arsenite mitogen activated protein kinase 14 Rattus norvegicus
2 Here, we report that sodium arsenite stimulates the protein expression and promoter activity of Bim(EL) in a p38-dependent manner. sodium arsenite mitogen activated protein kinase 14 Rattus norvegicus