Title : PPAR gamma regulates MITF and beta-catenin expression and promotes a differentiated phenotype in mouse melanoma S91.

Pub. Date : 2008 Jun

PMID : 18444964

1 Functional Relationships(s)
Compound Name
Protein Name
1 Beta-catenin, an MITF transcriptional activator, shows a similar pattern of decline during ciglitazone treatment, consistent with previous reports that activated PPAR gamma inhibits the Wnt/beta-catenin pathway through induction of beta-catenin proteasomal degradation. ciglitazone peroxisome proliferator activated receptor gamma Mus musculus