Title : [Latent autoimmune diabetes of adult or slim type 2 diabetes mellitus?].

Pub. Date : 2008 Mar

PMID : 18438542






3 Functional Relationships(s)
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1 Although controversy exists, the following diagnostic criteria for LADA are suggested: age between 25 and 65 years; absence of ketoacidosis or symptomatic hyperglycemia at diagnosis or immediately thereafter, without insulin requirement for 6-12 months; and presence of autoantibodies (especially GADA). gada ladinin 1 Homo sapiens
2 Autoimmunity and insulin resistance coexist in LADA and the contribution of these factors seems to be reflected in GADA titers. gada ladinin 1 Homo sapiens
3 Compared to GADA-negative diabetics, patients with LADA present a higher prevalence of other autoantibodies (anti-TPO, anti-21-hydroxylase and antibodies associated with celiac disease) and a higher frequency of genotypes and haplotypes indicating a risk for DM 1. gada ladinin 1 Homo sapiens