Title : Exercise restores endothelial function independently of weight loss or hyperglycaemic status in db/db mice.

Pub. Date : 2008 Jul

PMID : 18437348






1 Functional Relationships(s)
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1 RESULTS: Moderate-intensity exercise lowered body weight, increased mitochondrial manganese SOD (MnSOD) and both total and phosphorylated (Ser1177) endothelial nitric oxide synthase (eNOS) protein production; it also reduced whole-body (plasma 8-isoprostane) and tissue oxidative stress (nitrotyrosine immunostaining or protein carbonyl levels in the aorta). 3-nitrotyrosine nitric oxide synthase 3, endothelial cell Mus musculus