Title : Peroxisome proliferator-activated receptor gamma-mediated up-regulation of syndecan-1 by n-3 fatty acids promotes apoptosis of human breast cancer cells.

Pub. Date : 2008 Apr 15

PMID : 18413760






1 Functional Relationships(s)
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1 Using a luciferase gene driven by either a PPAR response element or a DR-1 site present in the SDC-1 promoter, reporter activities were enhanced by n-3 LDL, DHA, and PPAR gamma agonist, whereas activity of a luciferase gene placed downstream of a mutant DR-1 site was unresponsive. Docosahexaenoic Acids peroxisome proliferator activated receptor alpha Homo sapiens