Title : Entropy-driven cAMP-dependent allosteric control of inhibitory interactions in exchange proteins directly activated by cAMP.

Pub. Date : 2008 Jul 11

PMID : 18411261






1 Functional Relationships(s)
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1 Exchange proteins directly activated by cAMP (EPACs) are guanine nucleotide-exchange factors for the small GTPases Rap1 and Rap2 and represent a key receptor for the ubiquitous cAMP second messenger in eukaryotes. Guanine Nucleotides RAP1A, member of RAS oncogene family Homo sapiens