Title : Role of inducible nitric oxide synthase in induction of RhoA expression in hearts from diabetic rats.

Pub. Date : 2008 Jul 15

PMID : 18411229






1 Functional Relationships(s)
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1 AIMS: Recent studies from our laboratory demonstrated that increased expression of the small GTP-binding protein RhoA and activation of the RhoA/rho kinase (ROCK) pathway play an important role in the contractile dysfunction associated with diabetic cardiomyopathy in hearts from streptozotocin (STZ)-induced diabetic rats. Guanosine Triphosphate ras homolog family member A Rattus norvegicus