Pub. Date : 2005 Sep
PMID : 18404511
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Identification of a tyrosine residue responsible for N-acetylimidazole-induced increase of activity of ecto-nucleoside triphosphate diphosphohydrolase 3. | Tyrosine | ectonucleoside triphosphate diphosphohydrolase 3 | Homo sapiens |
| 2 | Chemical modification in combination with site-directed mutagenesis was used to identify a tyrosine residue responsible for the increase in ecto-nucleoside triphosphate diphosphohydrolase 3 (NTPDase3) nucleotidase activity after acetylation with a tyrosine-selective reagent, N-acetylimidazole. | Tyrosine | ectonucleoside triphosphate diphosphohydrolase 3 | Homo sapiens |
| 3 | Chemical modification in combination with site-directed mutagenesis was used to identify a tyrosine residue responsible for the increase in ecto-nucleoside triphosphate diphosphohydrolase 3 (NTPDase3) nucleotidase activity after acetylation with a tyrosine-selective reagent, N-acetylimidazole. | Tyrosine | ectonucleoside triphosphate diphosphohydrolase 3 | Homo sapiens |
| 4 | Chemical modification in combination with site-directed mutagenesis was used to identify a tyrosine residue responsible for the increase in ecto-nucleoside triphosphate diphosphohydrolase 3 (NTPDase3) nucleotidase activity after acetylation with a tyrosine-selective reagent, N-acetylimidazole. | Tyrosine | ectonucleoside triphosphate diphosphohydrolase 3 | Homo sapiens |
| 5 | Chemical modification in combination with site-directed mutagenesis was used to identify a tyrosine residue responsible for the increase in ecto-nucleoside triphosphate diphosphohydrolase 3 (NTPDase3) nucleotidase activity after acetylation with a tyrosine-selective reagent, N-acetylimidazole. | Tyrosine | ectonucleoside triphosphate diphosphohydrolase 3 | Homo sapiens |
| 6 | Thus, we speculate that the acetylation of tyrosine 252 might induce a subtle conformational change in NTPDase3, resulting in the observed increase in activity. | Tyrosine | ectonucleoside triphosphate diphosphohydrolase 3 | Homo sapiens |