Pub. Date : 2008 Oct
PMID : 18400332
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | XRCC1 polymorphisms and severe toxicity in lung cancer patients treated with cisplatin-based chemotherapy in Chinese population. | Cisplatin | X-ray repair cross complementing 1 | Homo sapiens |
| 2 | The predictability of DNA repair XRCC1 (X-ray repair cross-complementing group 1 protein) single nucleotide polymorphisms (SNPs) for cisplatin-based grades 3 and 4 chemotherapy-related toxicity in patients with newly diagnosed advanced lung cancer was evaluated. | Cisplatin | X-ray repair cross complementing 1 | Homo sapiens |
| 3 | The predictability of DNA repair XRCC1 (X-ray repair cross-complementing group 1 protein) single nucleotide polymorphisms (SNPs) for cisplatin-based grades 3 and 4 chemotherapy-related toxicity in patients with newly diagnosed advanced lung cancer was evaluated. | Cisplatin | X-ray repair cross complementing 1 | Homo sapiens |
| 4 | Our results suggested that patients carrying at least one variant XRCC1 Arg399Gln allele have a 2.5-fold increased risk of grade 3 or 4 gastrointestinal toxicity when treated with first-line cisplatin-based chemotherapy. | Cisplatin | X-ray repair cross complementing 1 | Homo sapiens |