Title : Modulation of astrocytic metabolic phenotype by proinflammatory cytokines.

Pub. Date : 2008 Jul

PMID : 18383346






1 Functional Relationships(s)
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1 As far as mechanisms for oxidative stress defence are concerned, we observed that treatment with IL-1beta+TNFalpha decreases cellular glutathione content and increases glutathione release into the extracellular space while stimulating superoxide anion and nitric oxide production as well as H(2)O(2) release. Superoxides tumor necrosis factor Mus musculus