Title : BRAFV600E mutation is associated with preferential sensitivity to mitogen-activated protein kinase kinase inhibition in thyroid cancer cell lines.

Pub. Date : 2008 Jun

PMID : 18381570






1 Functional Relationships(s)
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1 AZD6244 was more potent at inhibiting growth of NPA (BRAF +) than Cal62 (KRAS +) xenografts. AZD 6244 B-Raf proto-oncogene, serine/threonine kinase Homo sapiens