Pub. Date : 2008 Mar
PMID : 18380009
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Experiments with the embryonic stem cell line, ESC-B5, disclose that CTN induces apoptosis via several mechanisms, including ROS generation, increased cytoplasmic free calcium levels, intracellular nitric oxide production, enhanced Bax/Bcl-2 ratio, loss of mitochondrial membrane potential, cytochrome c release, activation of caspase-9 and caspase-3, and p21-activated protein kinase 2 and c-Jun N-terminal protein kinase activation. | Citrinin | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |