Title : Endoplasmic reticulum export of adrenergic and angiotensin II receptors is differentially regulated by Sar1 GTPase.

Pub. Date : 2008 Jun

PMID : 18378118






1 Functional Relationships(s)
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1 The cell-surface expression of alpha(2B)-AR, beta(2)-AR and AT1R, and receptor-mediated ERK1/2 activation were significantly attenuated by the GTP-bound mutant Sar1H79G, suggesting that export from the ER of these receptors is mediated through the Sar1-dependent COPII-coated vesicles. Guanosine Triphosphate adrenoceptor beta 2 Homo sapiens